With a noble aim of imparting education to all women KSN Government Degree & P.G. College for women was established in the year 1984 with B.A. & B.Com courses. Sri Kalluri Radha Krishnaiah, an industrialist and philanthropist contributed Rs. 2 lakhs in 1989 for the construction of old campus, near Municipal Corporation, Anantapur. The college is named after his parents Kasam Setty Subbaratnamma and Narayana Swamy, thus the college derived the acronym KSN Government Degree College for women. The present newly constructed building has wide campus with3.21 acres of land near JNTU College of Engineering, Anatapur. The college has equipped with well furnished infrastructure and a hostel within the campus. To improve physical fitness the college has a play ground. The college is affiliated to Sri Krishnadevaraya University, Anantapur. The college is governed by the authorities of University and Andhra Pradesh Government as stipulated in Universities Act and Government rules and regulations.
The college had B.A. & B.Com courses at the beginning, later B.Sc.(Mathematics, Physics, Computer Science) was included. And restructured courses: B.Com (Computer Applications) and B.A. (Computer Applications), B.A. (Advanced Urdu) and B.A. (Journalism) too were added.
The college has U.G.C recognition under 2 (f), 12(B) in 1992.